Thermo Fisher Scientific ATG4B Recombinant Rabbit Monoclonal Antibody (HL2348)
ATG4B 단백질을 인식하는 토끼 유래 재조합 단클론 항체로, Western blot 및 IHC(P) 분석에 적합합니다. 인간, 마우스, 랫트에 반응하며, Protein A로 정제된 액상 제품입니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
- Western Blot (WB): Assay-dependent
- Immunohistochemistry (Paraffin) (IHC (P)): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | HL2348 |
| Immunogen | Recombinant protein encompassing a sequence within the C-terminal region of human ATG4B (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3093839 |
Target Information
Cysteine protease ATG4B is an enzyme encoded by the ATG4B gene. Autophagy is a critical cellular homeostatic process that controls the turnover of damaged organelles and proteins. ATG4B is a deubiquitin-like protease that plays dual roles in the core machinery of autophagy. It cleaves the C-terminal amino acid of ATG8 family proteins (MAP1LC3, GABARAPL1, GABARAPL2, GABARAP) to expose a C-terminal glycine, which is essential for conjugation to phosphatidylethanolamine (PE) and membrane insertion, necessary for autophagy. ATG4B is mainly expressed in skeletal muscle, brain, heart, liver, and pancreas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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