Thermo Fisher Scientific CDK3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human CDK3. Recombinant protein control fragment (Product #RP-89774). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CDK3,uniProtId:Q00526-1,ncbiNodeId:9606,antigenRange:222-305,antigenLength:305,antigenImageFileName:PA5-52432_CDK3_Q00526-1_Rabbit.svg,antigenImageFileNamePDP:PA5-52432_CDK3_Q00526-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2639609

Product Specific Information

Immunogen sequence: PSEDTWPGVT QLPDYKGSFP KWTRKGLEEI VPNLEPEGRD LLMQLLQYDP SQRITAKTAL AHPYFSSPEP SPAARQYVLQ RFRH

Highest antigen sequence identity to the following orthologs: Mouse - 49%, Rat - 49%.

Target Information

CDK3/CyclinE1is a member of the cyclin-dependent protein kinase family and promotes entry into S phase, in part by activating members of the E2F family of transcription factors. CDK3 can also associate with cyclin C and phosphorylates the retinoblastoma 1 protein to promote exit from G0. The CDK3 gene has been mapped to chromosomal location of 17q22-qter, telomeric to the BRCA1 gene by somatic cell hybrids analysis. The presence of a single point mutation in the CDK3 gene from several Mus musculus strains commonly used in the laboratory has been reported.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.