Thermo Fisher Scientific PIMT Polyclonal Antibody
Thermo Fisher Scientific의 PIMT Polyclonal Antibody는 인간 TGS1 단백질의 중간 영역을 인식하는 토끼 다클론 항체입니다. Western blot에 적합하며, 고순도의 Affinity Chromatography로 정제되었습니다. PBS 및 sucrose buffer에 보관되며 연구용으로만 사용됩니다.
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Applications
- Western Blot (WB): 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human TGS1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2605912 |
Product Specific Information
- Peptide sequence: IDENPASDFD DSGSLLGFKY GSGQKYGGIP NFSHRQVRYL EKNVKLKSKY
- Sequence homology: Cow 92%; Dog 92%; Guinea Pig 93%; Horse 85%; Human 100%; Mouse 100%; Rabbit 93%; Rat 93%
Target Information
Catalyzes the two serial methylation steps for the conversion of 7-monomethylguanosine (m⁷G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m²,²,⁷G) cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m⁷G cap of U snRNAs leads to their concentration in nuclear foci, colocalization with coilin, and formation of canonical Cajal bodies (CBs). Plays a role in transcriptional regulation. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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