Thermo Fisher Scientific ASCC1 Monoclonal Antibody (OTI1H10), TrueMAB
ASCC1 단백질을 인식하는 마우스 단클론 항체. Western blot 및 유세포분석에 적합. 동결건조 형태로 제공되며, 재구성 시 약 1 mg/mL 농도 권장. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1H10 |
| Immunogen | Full length human recombinant protein of human ASCC1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The ASCC1 gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex, a transcriptional coactivator involved in gene transactivation by multiple transcription factors such as AP-1, NF-κB, and SRF.
The encoded protein contains an N-terminal KH-type RNA-binding motif essential for AP-1 transactivation by the ASC-1 complex.
Mutations in this gene are associated with Barrett’s esophagus and esophageal adenocarcinoma.
Multiple alternatively spliced transcripts encoding different isoforms have been observed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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