Thermo Fisher Scientific KANK1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Human KANK1. Recombinant protein control fragment (Product #RP-106684). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:KANK1,uniProtId:Q14678-1,ncbiNodeId:9606,antigenRange:815-959,antigenLength:1352,antigenImageFileName:PA5-65999_KANK1_Q14678-1_Rabbit.svg,antigenImageFileNamePDP:PA5-65999_KANK1_Q14678-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2663306

Product Specific Information

Immunogen sequence: APLGMMTGLDH YIERIQKLLA EQQTLLAENY SELAEAFGEP HSQMGSLNSQ LISTLSSINS VMKSASTEEL RNPDFQKTSL GKITGNYLGY TCKCGGLQSG SPLSSQTSQP EQEVGTSEGK PISSLDAFPT QEGTLSPVNL TDDQ

Highest antigen sequence identity to the following orthologs - mouse 77%, rat 79%.

Target Information

Ankyrins are membrane adaptor molecules that play important roles in the control of cytoskeleton formation by regulating actin polymerization. KANK1 (KN motif and ankyrin repeat domain-containing protein 1), also known as ANKRD15, is a 1,352 amino acid protein that contains at least 12 exons and 5 ANK repeats. It binds to beta-catenin and regulates its subcellular distribution. KANK1 is ubiquitously expressed and localizes to cytoplasm. It may function as a tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.