Thermo Fisher Scientific KANK1 Polyclonal Antibody
인간 KANK1 단백질을 인식하는 Rabbit Polyclonal 항체로, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 0.3 mg/mL 농도의 액상 형태. PBS(glycerol 포함) 버퍼에 보관하며, 장기 보관 시 -20°C 권장. 연구용 전용 제품.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
- Publications: N/A
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human KANK1. Recombinant protein control fragment (Product # RP-106684) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2663306 |
Product Specific Information
Immunogen sequence:
APLGMMTGLDH YIERIQKLLA EQQTLLAENY SELAEAFGEP HSQMGSLNSQ LISTLSSINS VMKSASTEEL RNPDFQKTSL GKITGNYLGY TCKCGGLQSG SPLSSQTSQP EQEVGTSEGK PISSLDAFPT QEGTLSPVNL TDDQ
- Highest antigen sequence identity to the following orthologs:
- Mouse: 77%
- Rat: 79%
Target Information
Ankyrins are membrane adaptor molecules that play important roles in the control of cytoskeleton formation by regulating actin polymerization.
KANK1 (KN motif and ankyrin repeat domain-containing protein 1), also known as ANKRD15, is a 1,352 amino acid protein that contains at least 12 exons and 5 ANK repeats.
It binds to beta-catenin and regulates its subcellular distribution. KANK1 is ubiquitously expressed and localizes to cytoplasm.
It may function as a tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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