Thermo Fisher Scientific MYOF Polyclonal Antibody
MYOF 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot과 ELISA에 사용 가능. 인간 및 생쥐 시료에 반응하며, 액상 형태로 제공. 세포막 및 핵막 단백질 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–190 of human MYOF (NP_0384791) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.47 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806086 |
Product Specific Information
Immunogen sequence:
MLRVIVESAS NIPKTKFGKP DPIVSVIFKD EKKKTKKVDN ELNPVWNEIL EFDLRGIPLD FSSSLGIIVK DFETIGQNKL IGTATVALKD LTGDQSRSLP YKLISLLNEK GQDTGATIDL VIGYDPPSAP HPNDLSGPSV PGMGGDGEED EGDEDRLDNA VRGPGPKGPV GTVSEAQLAR RLTKVKNSRR
Positive Samples: U-251MG, A-549, HeLa, NIH/3T3
Cellular Location: Cell membrane, Cytoplasmic vesicle membrane, Nucleus membrane, Single-pass type II membrane protein
Target Information
Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness affecting both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein structurally similar to dysferlin. It belongs to the ferlin family and associates with both plasma and nuclear membranes. Containing C2 domains, it is involved in calcium-mediated membrane fusion events, suggesting a role in membrane regeneration and repair. Two transcript variants encoding different isoforms have been identified, and other possible variants have been detected but not fully characterized.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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