ELK Biotechnology CD44 rabbit pAb
CD44 단백질을 인식하는 토끼 다클론 항체로, IF, WB, IHC, ELISA에 사용 가능. 세포막 단백질 검출에 적합하며 인간, 마우스, 랫트 시료에 반응. 고순도 IgG 형태로 -20°C에서 1년 보관 가능.
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CD44 rabbit pAb
제품 개요
CD44 rabbit pAb는 세포막 단백질 CD44를 인식하는 토끼 다클론 항체로, 세포 간 상호작용, 부착, 이동 등 다양한 생물학적 과정 연구에 활용됩니다. IF, WB, IHC, ELISA 등 다양한 응용에 적합합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | CD44 rabbit pAb |
| Alternative Names | CD44 antigen (CDw44; Epican; Extracellular matrix receptor III; ECMR-III; GP90 lymphocyte homing/adhesion receptor; HUTCH-I; Heparan sulfate proteoglycan; Hermes antigen; Hyaluronate receptor; Phagocytic glycoprotein 1; PGP-1; Phagocytic glycoprotein I; PGP-I; CD antigen CD44) |
| Applications | IF; WB; IHC; ELISA |
| Recommended Dilutions | IF: 1:50–200, WB: 1:500–2000, IHC: 1:50–300 |
| Immunogen | Synthesized peptide derived from human CD44 (AA range: 1105–1165) |
| Storage | -20°C / 1 year |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 120 kD |
| Gene ID (Human) | 960 |
| Human Swiss-Prot No. | P16070 |
| Species Reactivity | Human; Mouse; Rat |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein; Cell projection, microvillus; Colocalizes with actin in membrane protrusions at wounding edges; Co-localizes with RDX, EZR, and MSN in microvilli; Localizes to cholesterol-rich membrane-bound lipid raft domains. |
Background
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion, and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms. Alternative splicing contributes to the structural and functional diversity of this protein and may be related to tumor metastasis.
[provided by RefSeq, Jul 2008]
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