ELK Biotechnology CDY2 rabbit pAb

제품명

CDY2 rabbit pAb

제품 설명

CDY2 단백질은 크로모도메인과 히스톤 아세틸전이효소 촉매 도메인을 포함하는 단백질로, 주로 후기 정자세포의 핵 내에서 발현됩니다. 이 단백질은 히스톤의 고아세틸화 과정에 관여하며, 프로타민이 히스톤을 대체하는 DNA 포장 전환 과정에 중요한 역할을 합니다. 본 항체는 이러한 CDY2 단백질을 인식하는 rabbit polyclonal antibody로, Western blot(WB)에 적합합니다.

제품 사양

Background

This intronless gene encodes a protein containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. This protein is localized to the nucleus of late spermatids where histone hyperacetylation takes place. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein. Two nearly identical copies of this gene are found in a palindromic region on chromosome Y; this record represents the telomeric copy. Chromosome Y also contains a pair of closely related genes in another more telomeric palindrome as well as several related pseudogenes. (RefSeq, Jul 2008)