ELK Biotechnology CE120 rabbit pAb

제품명

CE120 rabbit pAb

제품 개요

CE120 rabbit pAb는 인간 CE120 단백질을 인식하는 다클론 항체로, 세포질 및 미세소관 조직 중심체(cytoskeleton, centrosome)에서의 단백질 위치 조절 연구에 활용됩니다. WB(웨스턴 블롯) 실험에 최적화되어 있으며, 인간 및 생쥐 시료에 반응합니다.

제품 정보

세포 내 위치 (Cellular Localization)

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Regulates the localization of TACC3 to the centrosome in neural progenitors in vivo.

유전자 배경 (Background)

This gene encodes a protein that functions in the microtubule-dependent coupling of the nucleus and the centrosome.
A similar protein in mouse plays a role in both interkinetic nuclear migration, which is a characteristic pattern of nuclear movement in neural progenitors, and in neural progenitor self-renewal.
Mutations in this gene are predicted to result in neurogenic defects.
Alternative splicing results in multiple transcript variants.
[provided by RefSeq, Oct 2009]