ELK Biotechnology CFC1 rabbit pAb
CFC1 단백질을 인식하는 토끼 다클론 항체로, WB에 적합합니다. 인간 및 생쥐 시료에 반응하며, 세포막 및 분비 단백질 연구에 활용됩니다. -20°C에서 1년 보관 가능하며, 고순도 IgG 형태로 제공됩니다.
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ELK Biotechnology CFC1 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | CFC1 rabbit pAb |
| Applications | WB |
| Recommended Dilutions | WB 1:500–2000 |
| Immunogen | Synthesized peptide derived from human CFC1 (AA range: 129–179) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 55997 |
| Human Swiss-Prot No | P0CG37 |
| Species Reactivity | Human, Mouse |
세포 내 위치 (Cellular Localization)
Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Does not exhibit a typical GPI-signal sequence. The C-terminal hydrophilic extension of the GPI-signal sequence reduces the efficiency of processing and could lead to the production of a secreted unprocessed form. This extension is found only in primates.
배경 (Background)
This gene encodes a member of the epidermal growth factor (EGF)–Cripto, Frl-1, and Cryptic (CFC) family, which are involved in signaling during embryonic development. Proteins in this family share a variant EGF-like motif, a conserved cysteine-rich domain, and a C-terminal hydrophobic region. The protein encoded by this gene is necessary for patterning the left-right embryonic axis. Mutations in this gene are associated with defects in organ development, including autosomal visceral heterotaxy and congenital heart disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. (RefSeq, Jul 2012)
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