ELK Biotechnology CRGA rabbit pAb

제품명

CRGA rabbit pAb

제품 설명

CRGA rabbit pAb는 인간 CRGA 단백질의 105–155 아미노산 서열에서 합성된 펩타이드를 면역원으로 제작된 토끼 폴리클로날 항체입니다.
이 항체는 Western Blot(WB) 분석에 적합하며, 인간, 마우스, 랫트 시료에서 반응합니다.

제품 사양

Background

Crystallins are separated into two classes: taxon-specific (enzyme) and ubiquitous. The ubiquitous class constitutes the major proteins of vertebrate eye lens, maintaining its transparency and refractive index.
Since lens fiber cells lose their nuclei during development, crystallins are produced and retained throughout life, making them extremely stable proteins.
Mammalian lens crystallins are divided into alpha, beta, and gamma families. Beta and gamma crystallins are also considered a superfamily.
Gamma-crystallins are highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions, and are differentially regulated after early development.
Four gamma-crystallin genes (γA–γD) and three pseudogenes (γE–γG) are tandemly organized in a gene cluster. Mutations or aging-related changes in these genes are implicated in cataract formation.
[provided by RefSeq, Jul 2008]