ELK Biotechnology DDX47 rabbit pAb

제품 개요

제품명: DDX47 rabbit pAb
공급업체: ELK Biotechnology

제품 설명

DDX47 단백질은 DEAD box 단백질 패밀리에 속하며, RNA 2차 구조 변형과 관련된 다양한 세포 과정에 관여하는 RNA 헬리케이스입니다. 이 항체는 인간 DDX47의 특정 펩타이드 서열(AA 86–136)을 면역원으로 하여 제작된 rabbit polyclonal antibody로, 웨스턴 블롯(WB) 분석에 적합합니다.
DDX47 단백질은 핵과 인핵에 주로 분포하며, 리보솜 생합성 과정에서 핵소체 조직 영역(nucleolar-organizing region)에 위치합니다.

제품 사양

Background

This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in various cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene can shuttle between the nucleus and the cytoplasm and has RNA-independent ATPase activity. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [RefSeq, Jul 2008]