ELK Biotechnology DNAJC2/MPP11 (phospho-Ser47) rabbit pAb
DNAJC2/MPP11 (phospho-Ser47) rabbit polyclonal antibody로 WB에 적합하며, 인산화된 Ser47 부위 인식. 핵과 세포질에 존재하는 단백질 검출에 활용. 인간, 마우스, 랫트 반응성. -20°C에서 1년 안정적 보관.
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제품명
DNAJC2/MPP11 (phospho-Ser47) rabbit pAb
공급업체
ELK Biotechnology
제품 개요
DNAJC2/MPP11 (phospho-Ser47) rabbit polyclonal antibody는 인산화된 Ser47 부위를 인식하는 항체로, 세포 내 핵 및 세포질에서 발현되는 단백질 검출에 적합합니다. 본 항체는 인간, 마우스, 랫트 시료에서 반응성을 보이며, Western blot(WB) 분석에 사용됩니다.
스펙 정보
| 항목 | 내용 |
|---|---|
| Product name | DNAJC2/MPP11 (phospho-Ser47) rabbit pAb |
| Alternative Names | DnaJ homolog subfamily C member 2 (M-phase phosphoprotein 11) (Zuotin-related factor 1) |
| Applications | WB |
| Recommended Dilutions | WB 1:1000–2000 |
| Immunogen | Synthesized phospho peptide around human DNAJC2 and MPP11 (Ser47) |
| Storage | -20°C / 1 year |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 68 kD |
| GeneID (Human) | 27000 |
| Human Swiss-Prot No | Q99543 |
| Cellular Localization | Nucleus, Cytoplasm (cytosol) |
| Species Reactivity | Human, Mouse, Rat |
Background
This gene belongs to the M-phase phosphoprotein (MPP) family. It encodes a phosphoprotein with a J domain and a Myb DNA-binding domain, localizing to both the nucleus and cytosol. The protein forms a heterodimeric complex that associates with ribosomes, functioning as a molecular chaperone for nascent polypeptide chains. It has been identified as a leukemia-associated antigen, with expression upregulated in leukemic blasts. Chromosomal aberrations involving this gene are linked to primary head and neck squamous cell tumors. A pseudogene exists on chromosome 6, and alternatively spliced variants encoding different isoforms have been described.
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