Thermo Fisher Scientific Human Plateable Hepatocytes, Transporter Qualified
Transporter 기능이 검증된 인간 동결보존 간세포로, 4°C 및 37°C에서 흡수 수송체 분석을 통해 평가됨. 높은 생존율과 형태 유지로 신뢰성 있는 in vitro/in vivo 상관 분석 가능. 단일 공여자 유래 세포로 품질 보증 테스트 완료. LN2 기화 상태로 배송 필요.
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- HMCPTS
- 판매단위
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Gibco™ Human Plateable Hepatocytes, Transporter Qualified
Plateable cryopreserved human hepatocytes assessed for transporter function using uptake transporter assays at both 4°C and 37°C.
Cells per vial: 4–8 million
Hepatocyte cultures were incubated with taurocholate and estradiol 17β glucuronide (E2-17G), substrates of the uptake and efflux transporters NTCP/BSEP and OATPs/MRP2. Accumulation rates and facilitated active uptake were calculated.
Get the Results You Need with GIBCO Hepatocytes
High-quality hepatocytes with high viabilities, proper cell morphology, and confirmed transporter function enhance the ability to draw in vitro/in vivo correlations and make sound decisions regarding a compound's fate.
Experienced technicians and proprietary isolation techniques combined with stringent release specifications ensure you receive the highest quality cryopreserved hepatocytes.
Each Lot is Tested For
- Viability ≥ 70%
- Attachment efficiency
- Monolayer formation and integrity
- Confluency > 80% on Day 4
- Tested for plating in 96-well format
- Phase I enzyme activities
- Transporter activity
- Bile canaliculi formation
- Relevant CYP450 polymorphisms
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Note:
These products require shipment in LN2 vapor dewars; therefore, additional fees may apply.
제품 사양
| 항목 | 내용 |
|---|---|
| 셀 유형 | Hepatocytes |
| Culture Type | Hepatocyte Cell Culture |
| 형태 | Cryopreserved |
| 종 | Human |
| 공여자 소스 | Single Donor |
| 셀 수 | 4–8 × 10⁶ |
| 제품 라인 | Gibco™ |
| 제품 유형 | Hepatocytes |
| 수량 | 1.5 mL vial |
| Unit Size | Each |
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