Gibco™

Human Plateable Hepatocytes, Transporter Qualified

Plateable cryopreserved human hepatocytes assessed for transporter function using uptake transporter assays at both 4°C and 37°C. Cells per vial:자세히 알아보기

Plateable cryopreserved human hepatocytes assessed for transporter function using uptake transporter assays at both 4°C and 37°C.

Cells per vial: 4-8 million

Hepatocyte cultures were incubated with taurocholate and estradiol 17β glucuronide (E2-17G), substrates of the uptake and efflux transporters NTCP/BSEP and OATPs/MRP2. Accumulation rates and facilitated active uptake were calculated.

Get the Results You Need with GIBCO Hepatocytes
High quality hepatocytes, with high viabilities, proper cell morphology, and transporter function increase the ability to draw in vitro⁄in vivo correlations and make sound decisions regarding a compound`s fate. Experienced technicians and proprietary isolation techniques combined with stringent release specifications ensure you receive the highest quality cryopreserved hepatocytes.

Each lot is tested for:
• Viability ≥ 70%
• Attachment efficiency
• Monolayer formation and integrity
• Confluency >80% on Day 4
• Tested for plating in 96 well format
• Phase I enzyme activities
• Transporter activity
• Bile canaliculi formation
• Relevant CYP450 polymorphisms

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Note:
These products require shipment in LN2 vapor dewars therefore additional fees may apply.

사양

셀 유형Hepatocytes

Culture TypeHepatocyte Cell Culture

형태Cryopreserved

종Human

공여자 소스Single Donor

셀 수4-8 x 106

제품라인Gibco™

제품 유형Hepatocytes

수량1.5 mL vial

Unit SizeEach