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Thermo Fisher Scientific BMI1 Monoclonal Antibody (BMI1, 2690)
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Human BMI1 단백질(aa 142-326)을 인식하는 mouse monoclonal antibody입니다. IHC(P) 및 Peptide Array에 사용 가능하며, Protein A/G로 정제된 액상 형태입니다. 4°C에서 보관하며 연구용으로만 사용됩니다.
- 카탈로그번호
- 648-MSM2-P0
- 판매단위
- pk
카탈로그
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마지막 업데이트 2025. 08. 02. 오후 12:41
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Thermo Fisher Scientific 648-MSM2-P0 BMI1 Monoclonal Antibody (BMI1, 2690) 20 ug pk판매 단위 pk ·
재고 확인 필요
441,900원VAT 포함 486,090원
Thermo Fisher Scientific · Thermo Fisher Scientific BMI1 Monoclonal Antibody (BMI1, 2690)
Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | BMI1, 2690 |
| Immunogen | Recombinant fragment (around aa 142–326) of human BMI1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): incubate antibody for 30 min at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
BMI1 is a component of the Polycomb group (PcG) multiprotein PRC1 complex, which maintains the transcriptionally repressive state of many genes, including Hox genes, throughout development.
The PRC1 complex acts via chromatin remodeling and histone modification, mediating monoubiquitination of histone H2A at Lys-119, thereby altering chromatin expressibility.
Within the PRC1 complex, BMI1 is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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