Thermo Fisher Scientific CTRP1 Monoclonal Antibody (C2)
CTRP1 단백질을 인식하는 Mouse monoclonal 항체로 Western blot, IHC, ICC/IF에 사용 가능. Human 및 Pig 시료 반응성. Protein A/G 정제, PBS/glycerol buffer에 보관. 대사 및 면역 관련 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–20 µg/mL |
| Immunocytochemistry (ICC/IF) | 5–20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Pig |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C2 |
| Immunogen | Recombinant Human C1QTNF1 protein, Arg26–Pro281 (Accession #Q9BXJ1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.05% Proclin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3090551 |
Target Information
Adipose tissue plays a major role in regulating physiological and pathological processes such as metabolism and immunity by producing and secreting bioactive molecules known as adipokines.
The adiponectin/ACRP30 family and its paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs 1–7), are highly conserved adipokines.
Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues and act mainly on liver and muscle to control glucose and lipid metabolism.
Structural analysis of adiponectin indicates an evolutionary link between TNF and C1q-containing proteins, suggesting a common ancestral innate immunity gene.
In obese (ob/ob) mice, RT-PCR analysis shows elevated mCTRP1 transcript levels in adipose tissue compared to normal mice.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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