Thermo Fisher Scientific NOTCH1 Polyclonal Antibody
NOTCH1 단백질을 인식하는 Rabbit Polyclonal Antibody로 인간 시료에 반응. Immunocytochemistry(ICC/IF)에 적합하며 항원 친화 크로마토그래피로 정제됨. PBS 및 글리세롤 완충액에 보존되어 안정적이며 연구용으로 사용 가능.
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Thermo Fisher Scientific NOTCH1 Polyclonal Antibody
Applications
- Immunocytochemistry (ICC/IF)
Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NOTCH1. Recombinant protein control fragment (Product #RP-107550) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2791900 |
Product Specific Information
Immunogen sequence:
GGSTSLNGQC EWLSRLQSGM VPNQYNPLRG SVAPGPLSTQ APSLQHGMVG PLHSSLAASA LSQMMSYQGL PSTRLATQPH LVQTQQVQPQ NLQMQQQNL
Target Information
The notch gene belongs to a family of epidermal growth factor (EGF)-like homeotic genes, which encode transmembrane proteins with a variable number of cysteine-rich EGF-like repeats in the extracellular region.
Four notch genes have been described in mammals: Notch1, Notch2, Notch3, and Notch4 (Int-3), which are implicated in the differentiation of the nervous system and other structures.
The EGF-like proteins Delta and Serrate have been identified as ligands of Notch1.
Mature Notch proteins are heterodimeric receptors derived from the cleavage of Notch pre-proteins into an extracellular subunit (NEC) containing multiple EGF-like repeats and a transmembrane subunit including intracellular region (Ntm).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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