Thermo Fisher Scientific AKT1 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1231)
Recombinant alpaca monoclonal antibody targeting human AKT1. Suitable for ICC/IF applications. High purity via metal-chelate chromatography. Provided in liquid form, 1 mg/mL concentration, PBS buffer without preservative. For research use only.
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Thermo Fisher Scientific AKT1 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1231)
Applications
- Immunocytochemistry (ICC/IF)
Tested Dilution: Assay-dependent
Publications: Refer to Thermo Fisher Scientific database for related studies.
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA1231 |
| Immunogen | Recombinant Human AKT1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Target Information
AKT1 (PKB alpha) is a serine/threonine kinase that regulates cell survival. The activated enzyme inhibits apoptosis and stimulates cell cycle progression by phosphorylating numerous targets in various cell types, including cancer cells. This kinase is activated by insulin, PI3K, IGF1, and other growth and survival factors. Akt promotes cell survival by inhibiting apoptosis through phosphorylation and inactivation of targets such as forkhead transcription factors and caspase-9. The AKT pathway is a major target for cancer drug discovery.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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