Thermo Fisher Scientific VPS34 Polyclonal Antibody
VPS34 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, WB 및 IHC에 적합합니다. 인간, 마우스, 랫트 반응성을 가지며, 동결건조 형태로 제공됩니다. 연구용으로만 사용되며, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
- 카탈로그번호
- OSV00085W-100UL
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:300–1:2,000
- Publications: View 3 publications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:1,000
- Publications: View 3 publications
Miscellaneous PubMed (Misc)
- Publications: View 3 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from internal region of human VPS34 conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: VPS34.
Target Information
PIK3C3 (hVPS34) is the sole class III member of the PI3 Kinase family. It phosphorylates phosphatidylinositol (PI) to produce phosphatidylinositol 3-phosphate [PI(3)P], which recruits downstream effectors containing FYVE and Phox domains to membranes.
PIK3C3 is involved in coupling nutrient signaling to mTOR and plays a role in autophagy and intracellular trafficking. It regulates degradative endocytic trafficking and is required for the abscission step in cytokinesis, likely in the context of PI3KC3-C2.
It is also involved in the transport of lysosomal enzyme precursors to lysosomes and is required for transport from early to late endosomes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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