Thermo Fisher Scientific NFKBID Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide between 91-119 amino acids from the N-terminal region of human NFKBID if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NFKBID,uniProtId:Q8NI38-1,ncbiNodeId:9606,antigenRange:91-119,antigenLength:313,antigenImageFileName:PA5-71595_NFKBID_Q8NI38-1_Rabbit.svg,antigenImageFileNamePDP:PA5-71595_NFKBID_Q8NI38-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.35 mg/mL

Purification

Protein A, Antigen affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2717449

Target Information

May regulate the expression of IL-2, IL-6, and other cytokines through regulation on NF-kappa-B activity. Functions in the regulation of inflammatory responses. May also regulate TCR-induced negative selection of thymocytes.I-kappa-BNS, the nuclear I-kappa-B-like protein encoded by Nfkbid, is required for the development of marginal zone and peritoneal B-1 B cells and additionally required for extrafollicular antibody responses to T-independent and -dependent immunogens.I-kappa-BNS has been identified as a member of the I-kappa-B family of NF-kappa-B inhibitors, which undergoes induction upon TCR signaling. I-kappa-BNS mediates both positive and negative gene regulation, depending on individual cell type and/or cytokine.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.