Thermo Fisher Scientific ARNT2 Polyclonal Antibody
Zebrafish에서 ARNT2 단백질을 검출하기 위한 Rabbit Polyclonal Antibody. Western blot에 최적화되어 있으며, 단백질 A 및 항원 친화 크로마토그래피로 정제됨. PBS 버퍼에 0.09% sodium azide 함유, 4°C 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Zebrafish |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 475-501 amino acids from the Central region of DANRE arnt2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.33 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2718486 |
Target Information
AhR, ARNT1, ARNT2, and BMAL1 are members of a family of transcription factors containing a basic helix-loop-helix motif and a common PAS motif.
The aromatic hydrocarbon receptor (AhR) is a ligand-dependent transcription factor that interacts with xenobiotic responsive elements (XREs) to activate several genes, including CYP1A1, glutathione S-transferase Ya subunit, and DT-diaphorase.
Ah receptor nuclear translocator proteins (Arnt1 or Arnt2) are required for ligand-dependent nuclear translocation of the Ah receptor and for binding to the XRE element.
BMAL1 (Brain and Muscle Arnt-like protein 1), also known as Arnt3, TIC, JAP3, or MOP-3, dimerizes with Clock and binds to the promoter region of mPer1, suggesting a role in the regulation of circadian oscillation in mammals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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