Thermo Fisher Scientific HOXB4 Recombinant Rabbit Monoclonal Antibody (23GB6620)
HOXB4 단백질을 인식하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체. 인간 및 랫트 시료에 반응하며 Western blot에 최적화됨. HEK293F 시스템에서 발현된 순수 IgG 형태로, 친화 크로마토그래피로 정제됨. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:1,000–1:5,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB6620 |
| Immunogen | A synthesized peptide derived from human HOXB4 (21–55AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
HOX homeobox genes play a role both in early stem cell function and in later stages of hematopoietic differentiation.
HOXB4 is a homeotic selector gene implicated in self-renewal of definitive hematopoietic stem cells (HSCs).
Expression of HOXB4 in primitive progenitors combined with culture on hematopoietic stroma induces a switch to the definitive HSC phenotype.
Activation of WNT signaling in HSCs increases HOXB4 expression, and perturbations of HOX gene expression can cause leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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