Thermo Fisher Scientific PLCG1 Polyclonal Antibody
Human PLCG1 단백질을 표적으로 하는 Rabbit Polyclonal Antibody로, IHC 및 ICC/IF에 적합. 항원 친화 크로마토그래피로 정제된 액상 형태이며, 높은 특이성과 재현성을 제공. 연구용으로만 사용 가능.
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Thermo Fisher Scientific PLCG1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PLCG1. Recombinant protein control fragment (Product #RP-102732). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2790502 |
Product Specific Information
Immunogen sequence:
SAYEEVPTSM MYSENDISNS IKNGILYLED PVNHEWYPHY FVLTSSKIYY SEETSSDQGN EDEEEPKEVS SSTELHSNEK WFHGKLGAG
Target Information
The mammalian Phospholipase Cγ (PLCγ) family has two closely related proteins, PLCγ1 and PLCγ2. The PLCγ isozymes have core structure domains and a unique array of domains containing an additional PH domain, two SH2 domains, and one SH3 domain. In response to extracellular stimuli such as hormones and growth factors, receptor tyrosine kinases (RTKs) phosphorylate and activate PLCγ. Activated PLCγ catalyzes hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) to produce second messenger molecules inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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