Thermo Fisher Scientific NAPRT1 Monoclonal Antibody (4A9)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

ELISA (ELISA)

1-5 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

4A9

Immunogen

NAPRT1 (NP_660202.2, 1 a.a. approximately 466 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NAPRT1,uniProtId:Q6XQN6-1,ncbiNodeId:9606,antigenRange:1-538,antigenLength:538,antigenImageFileName:H00093100-M01_NAPRT1_Q6XQN6-1_House_mouse.svg,antigenImageFileNamePDP:H00093100-M01_NAPRT1_Q6XQN6-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MALGYWRAGR ARDAAEFELF FRRCPFGGAF ALAAGLRDCV RFLRAFRLRD ADVQFLASVL PPDTDPAFFE HLRALDCSEV TVRALPEGSL AFPGVPLLQV SGPLLVVQLL ETPLLCLVSY ASLVATNAAR LRLIAGPEKR LLEMGLRRAQ GPDGGLTAST YSYLGGFDSS SNVLAGQLRG VPVAGTLAHS FVTSFSGSEV PPDPMLAPAA GEGPGVDLAA KAQVWLEQVC AHLGLGVQEP HPGERAAFVA YALAFPRAFQ GLLDTYSVWR SGLPNFLAVA LALGELGYRA VGVRLDSGDL LQQAQEIRKV FRAAAAQFQV PWLESVLIVV SNNIDEEALA RLAQEGSEVN VIGIGTSVVT CPQQPSLGGV YKLVAVGGQP RMKLTEDPEK QTLPGSKAAF RLLGSDGSPL MDMLQLAEEP VPQAGQELRV WPPGAQEPCT VRPAQVEPLL RLCLQQGQVA APPPSS

Target Information

Nicotinic acid (NA; niacin) is converted by nicotinic acid phosphoribosyltransferase (NAPRT; EC 2.4.2.11) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD), which serves as a coenzyme in cellular redox reactions and is an essential component of a variety of processes in cellular metabolism including response to stress (Hara et al., 2007).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.