Thermo Fisher Scientific MMP7 Monoclonal Antibody (OTI2E1), TrueMAB
인간 MMP7 단백질을 인식하는 마우스 단일클론 항체로, Western Blot에 적합합니다. TrueMAB 형식이며 비결합 상태로 제공됩니다. 고순도 친화 크로마토그래피 정제, 안정적인 PBS/BSA/glycerol 저장용액 구성. 연구용 전용 제품입니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 95–267 of human MMP7 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes like arthritis and metastasis.
Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases.
The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin, and casein, and differs from most MMP family members in that it lacks a conserved C-terminal protein domain.
This enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa.
The gene is part of a cluster of MMP genes localized to chromosome 11q22.3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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