Thermo Fisher Scientific Claudin 6 Polyclonal Antibody
Claudin 6 단백질을 인식하는 Rabbit Polyclonal 항체로, Human 및 Mouse 시료에 반응합니다. Western blot에 최적화되어 있으며, Protein A 및 항원 친화 크로마토그래피로 정제되었습니다. 세포 간 tight junction 연구용으로 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 130–159 amino acids from the central region of human CLDN6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2541705 |
Product Specific Information
This antibody is predicted to react with zebrafish based on sequence homology.
Target Information
Tight junctions are one form of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are composed of continuous networking strands in the outwardly facing cytoplasmic leaflet with complementary grooves in the inwardly facing extracytoplasmic leaflet.
This gene encodes a component of tight junction strands, belonging to the claudin family. The protein is an integral membrane protein and serves as one of the entry cofactors for hepatitis C virus. Gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member, CLDN9, on chromosome 16.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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