Thermo Fisher Scientific RPGR Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human RPGR. Recombinant protein control fragment (Product #RP-92146). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RPGR,uniProtId:Q92834-1,ncbiNodeId:9606,antigenRange:379-509,antigenLength:1020,antigenImageFileName:PA5-51607_RPGR_Q92834-1_Rabbit.svg,antigenImageFileNamePDP:PA5-51607_RPGR_Q92834-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2646715

Product Specific Information

Immunogen sequence: EINDTCLSVA TFLPYSSLTS GNVLQRTLSA RMRRRERERS PDSFSMRRTL PPIEGTLGLS ACFLPNSVFP RCSERNLQES VLSEQDLMQP EEPDYLLDEM TKEAEIDNSS TVESLGETTD ILNMTHIMSL N

Highest antigen sequence identity to the following orthologs: Mouse - 46%, Rat - 41%.

Target Information

This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.