Thermo Fisher Scientific NR0B1 Monoclonal Antibody (2F12)
NR0B1 단백질을 인식하는 Mouse IgG2a 단클론 항체로, 인간 시료에 반응합니다. ICC/IF 및 ELISA 실험에 적합하며, Affinity chromatography로 정제된 액상 형태입니다. 연구용으로만 사용되며, -20°C에서 보관합니다.
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Thermo Fisher Scientific NR0B1 Monoclonal Antibody (2F12)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 1 ng/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2F12 |
| Immunogen | NR0B1 (NP_000466, 361–470 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
IKCFLSKCWS LNISTKEYAY LKGTVLFNPD VPGLQCVKYI QGLQWGTQQI LSEHTRMTHQ GPHDRFIELN STLFLLRFIN ANVIAELFFR PIIGTVSMDD MMLEMLCTKI
Target Information
This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription mediated by the retinoic acid receptor. It also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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