Thermo Fisher Scientific PHLDA1 Polyclonal Antibody
PHLDA1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot에 적합하며 1:500~1:1,000 희석 비율로 사용 가능. 비결합형 액상 형태로 제공되며, -20°C에서 보관. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide derived from the internal region of human PHLA1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2555533 |
Target Information
Cytotoxic T lymphocyte (CTL)-mediated cytotoxicity is an important effector mechanism in immunosurveillance against virus-infected or transformed cells. Two mechanisms are known: a perforin-based process and a FAS-based mechanism involving the transducing molecule FAS (APO-1) and its ligand (FAS-L).
The human FAS (APO-1) protein is a 48 kDa cell surface glycoprotein belonging to the receptor family that includes CD40, nerve growth factor receptors, and tumor necrosis factor receptors.
FAS antigen is expressed in a broad range of lymphoid cell lines and is highly expressed in T cells following T cell receptor (TCR) crosslinking. A previously undescribed protein, TDAG51, restores activation-induced apoptosis in cells that have lost the ability to display Fas in response to activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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