원본
Thermo Fisher Scientific Mouse Noggin, Animal-Free Recombinant Protein, PeproTech
상품 한눈에 보기
동물 유래 성분이 없는 Mouse Noggin 재조합 단백질로, BMP-4 유도 활성 억제 평가에 사용됩니다. E. coli 발현 시스템에서 생산되며, ≥98%의 고순도와 낮은 엔도톡신 수준(<0.1 EU/µg)을 보장합니다. 발달 및 골형성 연구용으로 적합합니다.
- 카탈로그번호
- AF-250-38-xxxxx (3개 옵션)
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
3개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다회원가입 없이 바로 구매하세요
가입하지 않아도 비회원가로 구매하실 수 있습니다.
마지막 업데이트 2025. 08. 03. 오전 12:20
카탈로그 번호 · 상품 설명출고판매가담기
장비
Thermo Fisher Scientific AF-250-38-250UG Mouse Noggin, Animal-Free Recombinant Protein, PeproTech 250 ug pk판매 단위 pk
재고 1개
2,509,300원VAT 포함 2,760,230원
소모품
Thermo Fisher Scientific AF-250-38-50UG Mouse Noggin, Animal-Free Recombinant Protein, PeproTech 50 ug pk판매 단위 pk
재고 1개
999,100원VAT 포함 1,099,010원
Thermo Fisher Scientific AF-250-38-5UG Mouse Noggin, Animal-Free Recombinant Protein, PeproTech 5 ug pk판매 단위 pk ·
재고 확인 필요
169,200원VAT 포함 186,120원
Thermo Fisher Scientific · Thermo Fisher Scientific Mouse Noggin, Animal-Free Recombinant Protein, PeproTech
Applications
Functional Assay (Functional)
- Assay-dependent
In vitro Assay (IV)
- Refer to publications (9 available)
Miscellaneous PubMed (Misc)
- Refer to publication (1 available)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Mouse |
| Published species | Human, Mouse |
| Expression System | E. coli |
| Amino Acid Sequence | MQHYLHIRPA PSDNLPLVDL IEHPDPIFDP KEKDLNETLL RSLLGGHYDP GFMATSPPED RPGGGGGPAG GAEDLAELDQ LLRQRPSGAM PSEIKGLEFS EGLAQGKKQR LSKKLRRKLQ MWLWSQTFCP VLYAWNDLGS RFWPRYVKVG SCFSKRSCSV PEGMVCKPSK SVHLTVLRWR CQRRGGQRCG WIPIQYPIIS ECKCSC |
| Molecular Weight | 46.4 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | ≥98% (SDS-PAGE, HPLC) |
| Endotoxin Concentration | <0.1 EU/µg |
| Activity | Inhibits 5.0 ng/ml BMP-4 induced alkaline phosphatase production in ATDC5 cells. Expected ED50: 1.0–2.0 ng/ml. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Purified |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient |
Product Specific Information
- AF-250-38-1MG is provided as 2 × 500 µg (AF-250-38-500UG).
- Recombinant murine Noggin is a 46.4 kDa disulfide-linked homodimer, consisting of two 206 amino acid polypeptide chains.
- Shipped at ambient temperature.
- For storage, handling, and reconstitution, refer to the lot-specific Certificate of Analysis.
Target Information
Noggin plays a key role in developmental processes such as neural tube fusion and joint formation. Organ morphogenesis begins with epithelial stem cell downgrowth, regulated by WNT3A (β-catenin stabilization) and Noggin, a BMP inhibitor. Mutations in Noggin are associated with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1), both characterized by joint fusion defects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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문의
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