Thermo Fisher Scientific CDCA7L Monoclonal Antibody (OTI6C6), TrueMAB
CDCA7L 단백질을 인식하는 마우스 단클론 항체로, WB 및 IHC(P) 실험에 적합합니다. 고순도의 액상 항체이며, 1 mg/mL 농도로 제공됩니다. 세포 분열 관련 전사 조절 및 종양 연구에 활용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6C6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–337 of human CDCA7L produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cell division cycle-associated 7-like protein (CDCA7L, also known as RAM2) is a transcription factor involved in transcriptional regulation and apoptotic signaling pathways. It acts as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to its promoter region. CDCA7L plays an oncogenic role in mediating the transforming effect of MYC in medulloblastoma cells and may act downstream of P38-kinase and BCL-2, but upstream of CASP3 (caspase-3), CCND1 (cyclin D1), and E2F1.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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