
Thermo Fisher Scientific Human ACVR1 (ALK2), GST Tag Recombinant Protein
Human ACVR1 (ALK2) 단백질은 GST 태그가 부착된 재조합 키나아제 단백질로, 인체 유래 활성인 A 수용체 연구에 적합합니다. TGF-β 신호전달 관련 실험용으로 사용되며, -80°C에서 안정적으로 보관 가능합니다. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific Human ACVR1 (ALK2), GST Tag Recombinant Protein
Applications
- Kinase Assay (KA)
Tested Dilution: Assay-dependent
Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Expression System | Insect cells |
| Amino Acid Sequence | 145–509 |
| Tag | GST-tag |
| Molecular Weight | 69.1 kDa |
| Class | Recombinant |
| Type | Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Purified |
| Storage Buffer | 50 mM Tris, pH 7.5, 0.02% polysorbate 20, 50% glycerol, 150 mM NaCl, 0.5 mM EDTA, 2 mM DTT |
| Contains | No preservative |
| Storage Conditions | -80°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Dry ice |
Product Specific Information
- Spin briefly before use for maximum recovery.
- Aliquots below 20 µL are not recommended.
- Do not store kinase diluted.
- Properly stored at -80°C, guaranteed for 6 months from date of purchase.
- Protein Form: Catalytic
Target Information
Activin A receptor, type I (ACVR1) is a member of the transforming growth factor-beta (TGF-β) superfamily of signaling proteins.
ACVR1 signals a specific transcriptional response in concert with activin type II receptors.
Mutations in ACVR1 are associated with Fibrodysplasia Ossificans Progressiva (FOP), a rare genetic disorder causing abnormal bone formation in muscles, tendons, and connective tissues, as well as Epicanthus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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