Thermo Fisher Scientific TFPI Monoclonal Antibody (OTI3B1), TrueMAB
TFPI 단백질을 인식하는 마우스 모노클로날 항체로, Western blot 및 IHC(Paraffin) 실험에 적합합니다. 고순도 친화 크로마토그래피 정제, 1 mg/mL 농도, PBS/BSA/glycerol 완충액에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3B1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 29–304 of human TFPI produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Tissue factor pathway inhibitor (TFPI), also known as lipoprotein-associated coagulation inhibitor, is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation.
TFPI is glycosylated and predominantly found in the vascular endothelium and plasma, in both free forms and complexed with plasma lipoproteins.
The coagulation process initiates with the formation of a factor VIIa–TF complex, which activates proteases (factors IX and X) and leads to fibrin clot formation.
TFPI inhibits the activated factor X and VIIa–TF proteases in an autoregulatory loop.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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