
Thermo Fisher Scientific ZGPAT Polyclonal Antibody
Thermo Fisher Scientific의 ZGPAT Polyclonal Antibody는 인간 ZGPAT 단백질을 인식하는 토끼 유래 IgG 항체입니다. Western blot과 ICC/IF에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 세포 내 전사 억제 연구 및 EGFR 경로 관련 종양 억제 연구에 활용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human ZGPAT. Recombinant protein control fragment (Product #RP-105049) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664055 |
Product Specific Information
Immunogen sequence:
ALCPSLAVVGS DAVDSGTCSS AFAGWEVHTR GIGSRLLTKM GYEFGKGLGR HAEGRVEPIH AVVLPRGKSL DQCVETLQKQ TRVG
Highest antigen sequence identity to the following orthologs:
- Mouse: 78%
- Rat: 78%
Target Information
Transcription repressor that specifically binds the 5’-GGAG[GA]A[GA]A-3’ consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival, and migration. Its ability to repress genes of the EGFR pathway suggests it may act as a tumor suppressor and suppress breast carcinogenesis. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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