Thermo Fisher Scientific CD16 Monoclonal Antibody (J5511), Biotin
인간 CD16 항원을 인식하는 Mouse IgG1 단클론 항체로, Biotin으로 표지되어 있습니다. Flow Cytometry에 사용 가능하며, Protein A/G로 정제된 액상 형태입니다. NK 세포 연구 및 면역반응 분석에 적합합니다.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | J5511 |
| Immunogen | NK lymphocytes |
| Conjugate | Biotin |
| Form | Liquid |
| Purification | Protein A/G |
| Storage buffer | PBS with 0.2% carrier protein |
| Contains | 0.08% sodium azide |
| Storage conditions | 4°C, do not freeze |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1071350 |
Additional Formats
Target Information
CD16 encodes a receptor that recognizes the Fc portion of immunoglobulin G and is involved in the clearance of immune complexes from the circulation, as well as other functions such as cellular mediated cytotoxicity and enhancement of virus infections. This gene, FCGR3A, shares a high degree of similarity with another nearby gene, FCGR3B, located on chromosome 1.
The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, while FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage.
Mutations in this gene have been associated with immunodeficiency 20 and have been linked to susceptibility to recurrent viral infections, systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Diseases associated with FCGR3A include:
- Immunodeficiency 20
- Herpes Zoster
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
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