Thermo Fisher Scientific NFIA Monoclonal Antibody (OTI6F1), TrueMAB
인간 NFIA 단백질(aa 200-509)에 특이적인 단일클론 항체로 Western blot에 적합. 마우스 IgG1 형식이며 비결합형 액상 제품. 고순도 친화 크로마토그래피 정제, 안정적 PBS/BSA/glycerol 버퍼 구성. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:2,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6F1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 200–509 of human NFIA produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
NF-1, also designated CTF, is a family of CCAAT box binding proteins that stimulate DNA replication and activate transcription. Analysis of human NF-1 mRNA has revealed two forms of the NF-1 protein arising from alternate splicing of a single NF-1 gene. NF-1 binds its consensus DNA element as a homodimer via an amino-terminal DNA-binding domain and activates transcription through a proline-rich carboxy terminal transactivation domain. NF-1 recognizes and binds the adenovirus type 2 promoter and activates transcription of herpes simplex virus thymidine kinase genes. The NF-1 consensus element has been found in upstream promoter regions of multiple eukaryotic genes, including Ha-Ras, alpha-globin, HSP70, GRP78, Histone H1, myelin basic protein, and Xenopus laevis vitellogenin gene promoter.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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