Thermo Fisher Scientific TMEM2 Polyclonal Antibody
TMEM2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 인간 TMEM2 중간 영역 펩타이드를 면역원으로 제작되었으며, 다양한 종에 높은 상동성을 보입니다. 액상 형태로 제공되며, -20°C에서 보관합니다.
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Applications
- Western Blot (WB): 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human TMEM2 (aa 1–50) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2690345 |
Product Specific Information
This target displays homology in the following species:
Cow: 100% • Dog: 100% • Horse: 100% • Human: 100% • Mouse: 100% • Pig: 85% • Rabbit: 100% • Rat: 100%
Target Information
This gene encodes a type II transmembrane protein belonging to the interferon-induced transmembrane (IFITM) protein superfamily. The encoded protein functions as a cell surface hyaluronidase that cleaves extracellular high molecular weight hyaluronan into intermediate fragments before internalization and degradation in the lysosome. It also has an interferon-mediated antiviral function in humans through activation of the JAK-STAT signaling pathway. Activation of this gene by transcription factor SOX4 in breast cancer cells mediates the pathological effects of SOX4 on cancer progression. Naturally occurring mutations in this gene are associated with autosomal recessive non-syndromic hearing loss.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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