Thermo Fisher Scientific Phospho-mTOR (Ser2448) Recombinant Rabbit Monoclonal Antibody (mTORS2448-E11)
Phospho-mTOR (Ser2448) 특이성을 가진 재조합 토끼 모노클로날 항체로, 인간 및 생쥐 반응성. Flow Cytometry에 적합하며 다양한 형광 표지 형식으로 제공. 세포 성장 및 암 관련 mTOR 신호 연구에 활용 가능.
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Applications
- Flow Cytometry (Flow)
Tested Dilution: 1–1,000 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | mTORS2448-E11 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser2448 of human phospho mTOR |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 50% glycerol, 0.10% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897078 |
Additional Formats
Target Information
FRAP1 (mTOR) is a serine/threonine kinase that plays a critical role in cellular growth and proliferation. Perturbations in the mTOR/PI3-kinase/AKT pathway are associated with numerous forms of cancer. FRAP1 is also the target of rapamycin and its analogues, which are currently used as immunosuppressants and cancer therapeutics. Mutations affecting the gene result in Smith-Kingsmore syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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