Thermo Fisher Scientific CD104 Monoclonal Antibody (422325), Alexa Fluor 488
인간 CD104(Integrin beta 4)을 인식하는 마우스 단클론 항체로, Alexa Fluor 488 형광 표지. Flow Cytometry에 적합하며, 비특이적 교차 반응 없음. 단백질 A/G로 정제되어 높은 순도 유지. 4°C 암조건 보관, 동결 금지.
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Applications
- Flow Cytometry (Flow): 5 µL per million cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 422325 |
| Immunogen | CHO-derived recombinant human Integrin beta 4/CD104 (Asn28–Ser710) |
| Conjugate | Alexa Fluor™ 488 |
| Excitation / Emission Max | 499 / 520 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage buffer | Buffered saline solution with BSA |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C, store in the dark, DO NOT FREEZE |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609374 |
Additional Formats
- APC conjugate: MA5-23535
- Custom conjugation available upon request
Product Specific Information
In Western blots, no cross-reactivity with recombinant human Integrin beta 1, beta 2, beta 3, beta 5, beta 6, beta 8, or recombinant mouse Integrin beta 4 is observed.
Target Information
Integrins are heterodimeric transmembrane glycoprotein receptors composed of alpha and beta subunits. Different alpha/beta combinations determine ligand-binding specificity and mediate cell-matrix or cell-cell adhesion, influencing gene expression and cell growth.
The integrin beta 4 subunit forms a receptor for laminins, typically pairing with the alpha 6 subunit, and plays a key role in invasive carcinoma biology. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced variants encoding distinct isoforms are known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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