Thermo Fisher Scientific proNGF Polyclonal Antibody
proNGF에 특이적인 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IHC에 사용 가능. Mouse와 Rat 반응성 보유. Lyophilized 형태로 제공되며, 장기 보관 시 -20°C 권장. 연구용으로만 사용.
- 카탈로그번호
- OSN00061W-100UL
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific proNGF Polyclonal Antibody
Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from mouse proNGF conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity: proNGF.
Target Information
Nerve growth factor (NGF) influences the survival and differentiation of various neuronal and nonneuronal cells. The actions of this polypeptide result from binding to specific cell surface receptors, which exist as both high and low affinity sites.
Only the high affinity receptor is capable of signal transduction. Cross-linking studies with ¹²⁵I-NGF have shown that the high affinity receptor of rat PC12 cells forms an Mr 158,000 complex with NGF, while the low affinity receptor forms an Mr 100,000 complex.
Full-length cDNA clones for both the human and rat NGF receptor genes have been produced and sequenced, showing greater than 90% homology between the two species. NGF exhibits nerve growth stimulating activity and regulates growth and differentiation of sympathetic and certain sensory neurons. It also stimulates division and differentiation of sympathetic and embryonic sensory neurons.
Mutations in the NGF gene are associated with hereditary sensory and autonomic neuropathy type 5 (HSAN5), and dysregulation of NGF gene expression is linked to allergic rhinitis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.