Thermo Fisher Scientific GCP5 Polyclonal Antibody
Rabbit polyclonal antibody against human TUBGCP5. Suitable for Western blot applications. Supplied as a liquid, unconjugated form at 1 mg/mL. Store at -20°C. For research use only.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide derived from the internal region of human TUBGCP5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2555774 |
Target Information
The gamma-Tubulin complex is composed of gamma Tubulin and the associated proteins GCP2, GCP3, GCP4, GCP5, and GCP6, which are essential components of microtubule organizing centers. These components localize to both the centrosome, where they are involved in microtubule nucleation, and the cytoplasm, where they exist as soluble complexes that can be recruited to the centrosome as needed.
GCP5 (gamma-Tubulin complex component 5), also known as TUBGCP5, is a 1,024 amino acid member of the gamma-Tubulin complex and is highly expressed in heart and skeletal muscle. Defects in the gene encoding GCP5 are implicated in Prader-Willi syndrome (PWS), a rare genetic disorder associated with obesity, compulsive behavior, and lower intellectual ability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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