Thermo Fisher Scientific SYNE3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human SYNE3. Recombinant protein control fragment (Product #RP-101515). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SYNE3,uniProtId:Q6ZMZ3-1,ncbiNodeId:9606,antigenRange:197-292,antigenLength:975,antigenImageFileName:PA5-63090_SYNE3_Q6ZMZ3-1_Rabbit.svg,antigenImageFileNamePDP:PA5-63090_SYNE3_Q6ZMZ3-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2648132

Product Specific Information

Immunogen sequence: MKAEYDAVKA KAQKRVDLLE QVAREHEEYQ AGVDEFQLWL KAVVEKVNGC LGRNCKLPIT QRLSTLQDIA KDFPRGEESL ETLEEQSAGV IRNTSP

Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 77%.

Target Information

As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells. [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.