Thermo Fisher Scientific DORFIN/RNF19 Polyclonal Antibody
DORFIN/RNF19 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합. 인간, 생쥐, 랫트 반응성. Protein A 정제, 1 mg/mL 농도, -20°C 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human DORFIN/RNF19 (amino acids 621–720) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The DORFIN/RNF19 gene encodes a member of the ring between ring fingers (RBR) protein family. The encoded protein contains two RING-finger motifs and an in-between RING fingers motif. It functions as an E3 ubiquitin ligase localized to Lewy bodies and ubiquitylates synphilin-1, an interacting protein of alpha-synuclein in neurons. This protein may be involved in amyotrophic lateral sclerosis (ALS) and Parkinson’s disease. Alternative splicing results in multiple transcript variants.
[Provided by RefSeq, Jul 2013]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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