Thermo Fisher Scientific ABCA9 Polyclonal Antibody
ABCA9 단백질을 인식하는 Goat Polyclonal 항체로, IHC(P) 및 Flow Cytometry에 사용 가능. 합성 펩타이드(aa 599-613)를 면역원으로 제작. 0.5 mg/mL 농도의 액상 형태로 제공되며, TBS(pH 7.3), 0.5% BSA, 0.02% sodium azide 포함. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
| Flow Cytometry (Flow) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (QRVVQELEMENIQD) corresponding to the internal amino acids of ABCA9 (aa 599–613) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_10987288 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.
Target Information
ABCA9 (ATP-binding cassette, sub-family A (ABC1), member 9) is a 1,624 amino acid protein belonging to the ABC transporter superfamily and the ABCA family.
The ABC1 subfamily is the only major ABC subfamily exclusive to multicellular eukaryotes.
It is ubiquitously expressed, with high expression in heart, brain, and fetal tissues. ABCA9 is a multi-pass membrane protein containing two ABC transporter domains and exists as five alternatively spliced isoforms.
ABCA9 exhibits membrane subcellular localization and may play a role in monocyte differentiation and lipid homeostasis.
ABCA9 is up-regulated during monocyte differentiation into macrophages and down-regulated by cholesterol loading of macrophages.
Spanning 85 kb, ABCA9 contains 39 exons, with a non-coding first exon.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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