Thermo Fisher Scientific MSI2 Polyclonal Antibody
Human MSI2 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:500~1:2,000 희석으로 사용 가능. 보존제가 없는 액상 제품으로 Protein A 및 항원 친화 크로마토그래피로 정제됨. 줄기세포 유지와 관련된 MSI2 단백질 연구에 적합.
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the N-terminus of the Human MSI2 (UniProt ID: Q96DH6-1, length 328 aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | No preservative |
| Storage conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788100 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human MSI2.
Target Information
Msi2 (Musashi homolog 2), also known as MSI2H, is a 328 amino acid protein localized in the cytoplasm and contains two RNA recognition motif (RRM) domains. It is expressed ubiquitously at low levels and functions as an RNA-binding protein that regulates target mRNA expression, contributing to the proliferation and maintenance of stem cells in the central nervous system.
Msi2 is phosphorylated posttranslationally and upregulated in response to brain injury, suggesting a role in neural regeneration. Chromosomal aberrations involving the Msi2 gene are associated with chronic myeloid leukemia progression. Multiple isoforms exist due to alternative splicing.
Tissue specificity: Ubiquitous; detected at low levels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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