Thermo Fisher Scientific Tubulin beta 3/TUBB3 (Neuronal and Stem Cell Marker) Recombinant Rabbit Monoclonal Antibody (TUBB3/7090R)
신경 및 줄기세포 마커로 사용되는 재조합 토끼 단클론 항체. 인간 유래 Tubulin beta 3(TUBB3)에 특이적이며 WB, IHC, IE 등 다양한 응용 가능. 높은 순도와 안정성(24개월), 신경세포 분화 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2–4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Immunoelectrophoresis (IE) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | TUBB3/7090R |
| Immunogen | Synthetic peptide (aa 437–450) of human Tubulin beta 3 (TUBB3), coupled to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Antibody stability: 24 months
- Positive control: Human brain or testis
- Cellular localization: Cytoplasm
Specificity Comments:
This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene cause congenital fibrosis of the extraocular muscles type 3. In adults, tubulin beta 3 (TUBB3) is primarily expressed in neurons and is commonly used as a neuronal marker. It plays an important role in neuronal cell proliferation and differentiation.
Target Information
The betaIII-tubulin isoform is dominantly present in cells of neuronal origin and is one of the earliest markers of neuronal differentiation. It serves as a specific probe for neuronal cells and tumors originating from them. BetaIII-tubulin is most abundant in neuronal cells but is also detected in Sertoli cells of the testis and transiently in non-neuronal embryonic tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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