Thermo Fisher Scientific SGSM2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human SGSM2. Recombinant protein control fragment (Product #RP-93280). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SGSM2,uniProtId:O43147-1,ncbiNodeId:9606,antigenRange:647-716,antigenLength:1006,antigenImageFileName:PA5-55106_SGSM2_O43147-1_Rabbit.svg,antigenImageFileNamePDP:PA5-55106_SGSM2_O43147-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2647222

Product Specific Information

Immunogen sequence: HRDSTISNDV FISVDDLEPP EPQDPEDSRP KPEQEAGPGT PGTAVVEQQH SVEFDSPDSG LPSSRNYSVA

Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 86%.

Target Information

Small G proteins such as RAP and RAB proteins are the key molecules in intracellular signal transduction and vesicle transportation. A novel protein family small G protein signaling modulator (SGSM) consisting of three members SGSM1-3 bind to RAP and RAB family proteins. All three SGSM proteins possess both a RUN domain and a TBC domain. SGSM2 is a Rab9A effector that activates GTP hydrolysis by Rab32 and Rab33B proteins.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.