Thermo Fisher Scientific NPPB Monoclonal Antibody (OTI6F8), TrueMAB
인간 NPPB 단백질을 인식하는 마우스 단클론 항체로 Western blot, IHC, Luminex에 사용 가능. 고순도 친화 크로마토그래피 정제. 1 mg/mL 농도의 액상 형태로 제공되며, PBS/1% BSA/50% 글리세롤 버퍼에 보관. 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution | References |
|---|---|---|
| Western Blot (WB) | 1:2,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 | - |
| Luminex (LUM) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6F8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 27–102 of human NPPB produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene is a member of the natriuretic peptide family and encodes a secreted protein functioning as a cardiac hormone. The protein undergoes two cleavage events, one intracellular and another after secretion into the blood. Its biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and maintenance of cardiovascular homeostasis. Elevated levels in the bloodstream are indicative of heart failure. Mutations in this gene have been linked to postmenopausal osteoporosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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