Thermo Fisher Scientific PDE10A Polyclonal Antibody
PDE10A 단백질에 특이적인 Thermo Fisher Scientific의 Rabbit Polyclonal 항체입니다. Western blot, IHC, ICC 등 다양한 응용에 사용 가능하며, Human, Mouse, Rat에 반응합니다. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:20,000 | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 547–779 of Human PDE10A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.97 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2548767 |
Product Specific Information
- Recommended positive controls: HCT116, mouse brain, rat brain, Myc-DDK-tagged PDE10A-transfected 293T
- Predicted reactivity: Mouse (98%), Rat (98%), Zebrafish (84%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Various cellular responses are regulated by the second messengers cAMP and cGMP.
Phosphodiesterases, such as PDE10A, eliminate cAMP- and cGMP-mediated intracellular signaling by hydrolyzing the cyclic nucleotide to the corresponding nucleoside 5-prime monophosphate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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