Thermo Fisher Scientific H3K79me2 Polyclonal Antibody
Rabbit polyclonal antibody recognizing dimethylated H3K79 for chromatin and epigenetic research. Validated for WB, ICC/IF, and ChIP applications. Affinity purified, liquid form, suitable for human samples. For research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1 µg/mL |
| ChIP assay (ChIP) | 1.5 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Methylated peptide (Lys79) corresponding to Human H3 (aa 75–83) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS (pH 7.2) with 0.1% BSA and 30% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2532795 |
Product Specific Information
These rabbit polyclonal antibodies are developed by immunizing animals with specific proteins or peptides. The antibodies are purified by affinity chromatography and tested for functionality in relevant research applications.
They are intended for Research Use Only, non-hazardous and non-infectious.
Because the target is conserved across species, cross-reactivity may occur with other organisms.
Target Information
Histone H3 is a DNA-binding protein found in the chromatin of all eukaryotic cells. Together with other core histones, it forms nucleosomes that regulate DNA accessibility.
Histones play key roles in transcription regulation, DNA repair, replication, and chromosomal stability.
The N-terminal tail of histone H3 can undergo post-translational modifications such as methylation, acetylation, and phosphorylation, which influence chromatin structure and gene expression.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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